Author Archives: Scott Alexander

Age Gaps And Birth Order Effects

[Parts of this post have since been shown to be wrong, as explained in this post. I endorse this reanalysis as better than the current post.] Psychologists are split on the existence of “birth order effects”, where oldest siblings will … Continue reading

Is There A Case For Skepticism Of Psychedelic Therapy?

There’s been an explosion of interest in the use of psychedelics in psychiatry. Like everyone else, I hope this works out. But recent discussion has been so overwhelmingly positive that it’s worth reviewing whether there’s a case for skepticism. I … Continue reading

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5-HTTLPR: A Pointed Review

In 1996, some researchers discovered that depressed people often had an unusual version of the serotonin transporter gene 5-HTTLPR. The study became a psychiatric sensation, getting thousands of citations and sparking dozens of replication attempts (page 3 here lists 46). … Continue reading

OT127: Openinsula Thread

This is the bi-weekly visible open thread (there are also hidden open threads twice a week you can reach through the Open Thread tab on the top of the page). Post about anything you want, but please try to avoid … Continue reading

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Little Known Types Of Eclipse

A lunar eclipse occurs when the Earth gets between the Moon and the Sun. A solar eclipse occurs when the Moon gets between the Earth and the Sun. A terrestrial eclipse occurs when the Earth gets between you and the … Continue reading

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Update To Partial Retraction Of Animal Value And Neuron Number

[Update 10/2/23: See also here] A few weeks ago I published results of a small (n = 50) survey showing that people’s moral valuation of different kinds of animals scaled pretty nicely with the animals’ number of cortical neurons (see … Continue reading

Buspirone Shortage In Healthcaristan SSR

(Epistemic status: Unsure on details. Some post-publication edits 5/1 to make this less strident.) I. There is a national shortage of buspirone. Buspirone is a 5HT-1 agonist used to control anxiety. Unlike most psychiatric drugs, it’s in a class of … Continue reading

Links 4/2019

[Epistemic status: I have not independently verified each link. On average, about two of the links in each links post turn out to be wrong or misleading, as found by commenters. I correct these as I see them, but can’t … Continue reading

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1960: The Year The Singularity Was Cancelled

[Epistemic status: Very speculative, especially Parts 3 and 4. Like many good things, this post is based on a conversation with Paul Christiano; most of the good ideas are his, any errors are mine.] I. In the 1950s, an Austrian … Continue reading

OT126: Ovum Thread

Happy Easter and Passover! This is the bi-weekly visible open thread (there are also hidden open threads twice a week you can reach through the Open Thread tab on the top of the page). Post about anything you want, but … Continue reading

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