Tag Archives: genetics

5-HTTLPR: A Pointed Review

In 1996, some researchers discovered that depressed people often had an unusual version of the serotonin transporter gene 5-HTTLPR. The study became a psychiatric sensation, getting thousands of citations and sparking dozens of replication attempts (page 3 here lists 46). … Continue reading

The Omnigenic Model As Metaphor For Life

The collective intellect is change-blind. Knowledge gained seems so natural that we forget what it was like not to have it. Piaget says children gain long-term memory at age 4 and don’t learn abstract thought until ten; do you remember … Continue reading

SSC Journal Club: Childhood Trauma And Cognition

This month’s American Journal of Psychiatry includes Danese et al, Origins Of Cognitive Deficits In Victimized Children. Previous studies had found that abused children had lower IQ. They concluded that the severe stress of being abused must decrease brain function. … Continue reading

Antidepressant Pharmacogenomics: Much More Than You Wanted To Know

[Epistemic status: very uncertain. Not to be taken as medical advice. Talk to your doctor before deciding whether or not to get any tests.] I. There are many antidepressants in common use. With a few exceptions, none are globally better … Continue reading

Myers’ Race Car Versus The General Fitness Factor

[Epistemic status: I am not a geneticist, and even the geneticists I know aren’t sure about a lot of this. Take as speculation only.] I. PZ Myers argues against Stephen Hsu’s genetic engineering proposal here – a disappointing attitude toward … Continue reading

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Non-Shared Environment Doesn’t Just Mean Schools And Peers

[Epistemic status: uncertain. Everything in here seems right, but I haven’t heard other people/experts in the field talk about this nearly as much as I would expect them to if it were true. Obviously amount of variability attributable to environment … Continue reading

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Things I Don’t Understand About Genetics (A Non-Exhaustive List)

A couple months ago the Genetic Association Consortium’s study on SNPs for intelligence raised an important question: should all of our genetics studies be performed by organizations whose acronyms are also amino acid codons? And aspartic acid? Really? Kind of … Continue reading

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