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Tag Archives: psychiatry

Antidepressant Pharmacogenomics: Much More Than You Wanted To Know

[Epistemic status: very uncertain. Not to be taken as medical advice. Talk to your doctor before deciding whether or not to get any tests.] I. There are many antidepressants in common use. With a few exceptions, none are globally better … Continue reading

Book Review: Mount Misery

[Content warning: psychiatric abuse (especially around borderline personality), rape, spoilers for Mount Misery] I. Last month I reviewed Samuel Shem’s House of God. The sequel, Mount Misery, is about his time training in psychiatry. This is obviously relevant to my … Continue reading

SSC Journal Club: Mental Disorders As Networks

I. Suppose you have sniffles, fatigue, muscle aches, and headache. You go to the doctor, who diagnoses you with influenza and gives you some Tamiflu. There’s some complicated statistics going on here. Your doctor has noticed some observable variables (sniffles, … Continue reading

The Alzheimer Photo

A professor recently brought my attention to this photo of Alois Alzheimer and his colleagues in Munich (source): Alzheimer is the very-German-looking guy with the silly mustache third from the right on the top. Far right is Friedrich Lewy, discoverer … Continue reading

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Somewhat Against Psychiatric Conditions As Domestication Failure

[Epistemic status: Not sure if I’m arguing against a straw man here and my conclusion is what the researchers meant all along.] I. Benitez-Burraco and Lattanzi theorize that autism and schizophrenia are anomalies in the human self-domestication process. I’ll try … Continue reading

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Tolerance Troubles

[Not meant as a claim that science doesn’t know something. More of an admission that I don’t know some things, and a hope to be informed about them by someone who does.] Everyone knows about tolerance. The first time you … Continue reading

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Book Review: PiHKaL

I. PiHKAL (“Phenylethylamines I Have Known And Loved”), subtitled “A Chemical Love Story”, is the autobiography of Alexander and Ann Shulgin. Alexander Shulgin was a chemist who invented lots of new psychedelic drugs. Ann was his wife. Together they discuss … Continue reading

3/4

Related: 1/4, 2/4 [Content warning: psychiatry, suicide. Note that all stories involving patients are mixtures of several different people which have been obfuscated and changed around in order to protect confidentiality. The ethical standard I have heard in this situation … Continue reading

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Book Review: Unlearn Your Pain

[Content warning: discussion of chronic pain and related conditions, and the debate over whether some of them may be psychological in origin. None of this is medical advice or a recommendation to start or stop any form of therapy. Low … Continue reading

Ketamine Research In A New Light

[Preliminary drawing of very far-out conclusions from research that hasn’t even been 100% confirmed yet] A few weeks ago, Nature published a bombshell study showing that ketamine’s antidepressant effects were actually caused by a metabolite, 2S,6S;2R,6R-hydroxynorketamine (don’t worry about the … Continue reading

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