Tag Archives: psychiatry

Book Review: The Body Keeps The Score

I. The Body Keeps The Score is a book about post-traumatic stress disorder. The author, Bessel van der Kolk, helped discover the condition and lobby for its inclusion in the DSM, and the brief forays into that history are the … Continue reading

Against Against Pseudoaddiction

I. “Pseudoaddiction” is one of the standard beats every article on the opioid crisis has to hit. Pharma companies (the story goes) invented a concept called “pseudoaddiction”, which looks exactly like addiction, except it means you just need to give … Continue reading

Lots Of People Going Around With Mild Hallucinations All The Time

[Related to: Relaxed Beliefs Under Psychedelics And The Anarchic Brain, HPPD And The Specter Of Permanent Side Effects] I. Hallucinogen persisting perceptual disorder is a condition where people who take psychedelics continue hallucinating indefinitely. Estimates of prevalence range from about … Continue reading

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SSC Journal Club: Relaxed Beliefs Under Psychedelics And The Anarchic Brain

[Thanks to Sarah H. and the people at her house for help understanding this paper] The predictive coding theory argues that the brain uses Bayesian calculations to make sense of the noisy and complex world around it. It relies heavily … Continue reading

Attempted Replication: Does Beef Jerky Cause Manic Episodes?

Last year, a study came out showing that beef jerky and other cured meats, could trigger mania in bipolar disorder (paper, popular article). It was a pretty big deal, getting coverage in the national press and affecting the advice psychiatrists … Continue reading

Know Your Gabapentinoids

The gabapentinoids are a class of drugs vaguely resembling the neurotransmitter GABA. Although they were developed to imitate GABA’s action, later research discovered they acted on a different target, the A2D subunit of calcium channels. Two gabapentinoids are approved by … Continue reading

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Do People Like Their Mental Health Care?

Along with more specific questions, I asked people who took the SSC survey to rate their experience with the mental health system on a 1 – 10 scale. About 5,000 people answered. On average, they rated their experience with psychotherapy … Continue reading

The APA Meeting: A Photo-Essay

The first thing you notice at the American Psychiatric Association meeting is its size. By conservative estimates, a quarter of the psychiatrists in the United States are packed into a single giant San Francisco convention center, more than 15,000 people. … Continue reading

Is There A Case For Skepticism Of Psychedelic Therapy?

There’s been an explosion of interest in the use of psychedelics in psychiatry. Like everyone else, I hope this works out. But recent discussion has been so overwhelmingly positive that it’s worth reviewing whether there’s a case for skepticism. I … Continue reading

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5-HTTLPR: A Pointed Review

In 1996, some researchers discovered that depressed people often had an unusual version of the serotonin transporter gene 5-HTTLPR. The study became a psychiatric sensation, getting thousands of citations and sparking dozens of replication attempts (page 3 here lists 46). … Continue reading