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Tag Archives: medicine

Against Against Pseudoaddiction

I. “Pseudoaddiction” is one of the standard beats every article on the opioid crisis has to hit. Pharma companies (the story goes) invented a concept called “pseudoaddiction”, which looks exactly like addiction, except it means you just need to give … Continue reading

More Confounders

[Epistemic status: Somewhat confident in the medical analysis, a little out of my depth discussing the statistics] For years, we’ve been warning patients that their sleeping pills could kill them. How? In every way possible. People taking sleeping pills not … Continue reading

Buspirone Shortage In Healthcaristan SSR

(Epistemic status: Unsure on details. Some post-publication edits 5/1 to make this less strident.) I. There is a national shortage of buspirone. Buspirone is a 5HT-1 agonist used to control anxiety. Unlike most psychiatric drugs, it’s in a class of … Continue reading

Ketamine: Now By Prescription

Last week the FDA approved esketamine for treatment-resistant depression. Let’s review how the pharmaceutical industry works: a company discovers and patents a potentially exciting new drug. They spend tens of millions of dollars proving safety and efficacy to the FDA. … Continue reading

Marijuana: An Update

[Originally to be titled “Marijuana: I Was Wrong”, but looking back I was suitably careful about everything, and my reward is not having to say that.] Five years ago, I reviewed the potential costs and benefits of marijuana legalization and … Continue reading

Anxiety Sampler Kits

The best thing about personalized medicine is that it’s obviously right. The worst thing is we mostly have no idea how to do it. We know that different people respond to different treatments. But outside a few special cases like … Continue reading

Nighttime Ventilation Survey Results

Thanks to the 129 people who tried altering their nighttime carbon dioxide levels after my post on this, and who reported back to me. There was no difference between people who pre-registered for the study and people who didn’t, on … Continue reading

Carbon Dioxide: An Open Door Policy

[Content note: reading this post might cause feelings of suffocation or provoke panic attacks in susceptible individuals. Epistemic status is very speculative.] Last month I moved into a small cottage behind a big group house. The cottage is lovely. The … Continue reading

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Cancer Progress: Much More Than You Wanted To Know

Official statistics say we are winning the War on Cancer. Cancer incidence rates, mortality rates, and five-year-survival rates have generally been moving in the right direction over the past few decades. More skeptical people offer an alternate narrative. Cancer incidence … Continue reading

Did A Melatonin Patent Inspire Current Dose Confusion?

Yesterday I wrote about melatonin, mentioning that most drugstore melatonin supplements were 10x or more the recommended dose. A commenter on Facebook pointed me to an interesting explanation of why. Dr. Richard Wurtman, an MIT scientist who helped discover melatonin’s … Continue reading