THE JOYFUL REDUCTION OF UNCERTAINTY

Tag Archives: psychiatry

Diametrical Model Of Autism And Schizophrenia

One interesting thing I took from Evolutionary Psychopathology was a better understanding of the diametrical theory of the social brain. There’s been a lot of discussion over whether schizophrenia is somehow the “opposite” of autism. Many of the genes that … Continue reading

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Del Giudice On The Self-Starvation Cycle

[Content note: eating disorders] Anorexia has a cultural component. I’m usually reluctant to assume anything is cultural – every mediocre social scientist’s first instinct is always to come up with a cultural explanation which is simple, seductive, flattering to all … Continue reading

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Book Review: Evolutionary Psychopathology

I. Evolutionary psychology is famous for having lots of stories that make sense but are hard to test. Psychiatry is famous for having mountains of experimental data but no idea what’s going on. Maybe if you added them together, they … Continue reading

Ketamine: An Update

In 2016, I wrote Ketamine Research In A New Light, which discussed the emerging consensus that, contra existing theory, ketamine’s rapid-acting antidepressant effects had nothing to do with NMDA at all. I discussed some experiments which suggested they might actually … Continue reading

SSRIs: An Update

Four years ago I examined the claim that SSRIs are little better than placebo. Since then, some of my thinking on this question has changed. First, we got Cipriani et al’s meta-analysis of anti-depressants. It avoids some of the pitfalls … Continue reading

Cognitive Enhancers: Mechanisms And Tradeoffs

[Epistemic status: so, so, so speculative. I do not necessarily endorse taking any of the substances mentioned in this post.] There’s been recent interest in “smart drugs” said to enhance learning and memory. For example, from the Washington Post: When … Continue reading

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The Chamber of Guf

[I briefly had a different piece up tonight discussing a conference, but the organizers asked me to hold off on writing about it until they’ve put up their own synopsis. It will be back up eventually; please accept this post … Continue reading

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Anxiety Sampler Kits

The best thing about personalized medicine is that it’s obviously right. The worst thing is we mostly have no idea how to do it. We know that different people respond to different treatments. But outside a few special cases like … Continue reading

Treating The Prodrome

A prodrome is an early stage of a condition that might have different symptoms than the full-blown version. In psychiatry, the prodrome of schizophrenia is the few-months-to-few-years period when a person is just starting to develop schizophrenia and is acting … Continue reading

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The Omnigenic Model As Metaphor For Life

The collective intellect is change-blind. Knowledge gained seems so natural that we forget what it was like not to have it. Piaget says children gain long-term memory at age 4 and don’t learn abstract thought until ten; do you remember … Continue reading