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	<title>Comments on: More Links for November</title>
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	<description>In a mad world, all blogging is psychiatry blogging</description>
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		<title>By: US</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-24135</link>
		<dc:creator><![CDATA[US]]></dc:creator>
		<pubDate>Tue, 10 Dec 2013 12:57:33 +0000</pubDate>
		<guid isPermaLink="false">http://slatestarcodex.com/?p=1125#comment-24135</guid>
		<description><![CDATA[&quot;Old people seem to be almost bimodal – you’ll get 80 year olds who are really decrepit, demented, and on twenty medications, but by the time you get past 100 or so, they seem to be universally pretty healthy. This surprises me. It’s almost as if there’s some gene for stay-healthy-in-old-age, and everyone without the gene dies off early so that all the really really old people are in perfect health until they die of natural causes.&quot;

This doesn&#039;t sound right to me. A few observations:

&quot;A long-held myth regarding development is that as people age, they all become alike. This view is refuted by the third principle of adult development and aging, which asserts that as people age, they become more different from each other rather than more alike. With increasing age, older adults become a more diverse segment of the population in terms of their physical functioning, psychological performance, and conditions of living. [...] Research continues to underscore the notion that individuals continue to become less alike with age. Such findings suggest that diversity becomes an increasingly prominent theme during the adult years, a point we will continue to focus on throughout this book.&quot;

From &lt;a href=&quot;http://www.amazon.com/Adult-Development-Aging-Biopsychosocial-Perspectives-ebook/dp/B005H8M3XM&quot; rel=&quot;nofollow&quot;&gt;Whitbourne &amp; Whitbourne&lt;/a&gt;. Not bimodality, just greater variance. More:

&quot;Over a 3-month period, even a moderate training program can augment muscle strength and maximal aerobic power by 20% or more, 25,26 — equivalent to a reversal of approximately 20 years of normal aging.26 [...] The muscle force and aerobic power required to undertake many of the tasks important to the independence of an elderly person (for example, rising from a chair or climbing a flight of stairs) are almost directly proportional to an individual’s body mass. Thus, a 10% reduction in body mass will effectively increase muscle strength and maximal aerobic power by some 10%, equivalent to a 10-year reversal of the effects of aging. [...] It has been suggested that declines in functional capacity with age reflect age-related reductions in physical activity. Inactivity has been estimated to account for 50% of the age-related loss in function.&quot; 

That is to say that to the extent that large differences exist, environmental factors - in particular physical activity - remain really important even in old age - i.e. it&#039;s not just genetics. Quotes above are from &lt;a href=&quot;http://books.google.dk/books/about/Gender_Physical_Activity_and_Aging.html?id=JgsqxTHeTiYC&amp;redir_esc=y&quot; rel=&quot;nofollow&quot;&gt;Gender, Physical Activity, and Aging&lt;/a&gt;, by Shephard et al).

Also, on the same topic &lt;a href=&quot;http://www.sciencedirect.com/science/article/pii/S0140673695915567&quot; rel=&quot;nofollow&quot;&gt;one meta-review&lt;/a&gt; on Alzheimer&#039;s in the very old found that 40% of those aged 95 suffered from Alzheimer&#039;s. It was noteworthy that risk didn&#039;t increase past that point (i.e. in people older than 95), but when 2 out of 5 of the people you&#039;re looking at suffer from dementia I&#039;m not sure &#039;pretty healthy&#039; is the best way to describe that population. The proportion of males having (prostate) cancer at that age is also, well, high...]]></description>
		<content:encoded><![CDATA[<p>&#8220;Old people seem to be almost bimodal – you’ll get 80 year olds who are really decrepit, demented, and on twenty medications, but by the time you get past 100 or so, they seem to be universally pretty healthy. This surprises me. It’s almost as if there’s some gene for stay-healthy-in-old-age, and everyone without the gene dies off early so that all the really really old people are in perfect health until they die of natural causes.&#8221;</p>
<p>This doesn&#8217;t sound right to me. A few observations:</p>
<p>&#8220;A long-held myth regarding development is that as people age, they all become alike. This view is refuted by the third principle of adult development and aging, which asserts that as people age, they become more different from each other rather than more alike. With increasing age, older adults become a more diverse segment of the population in terms of their physical functioning, psychological performance, and conditions of living. [&#8230;] Research continues to underscore the notion that individuals continue to become less alike with age. Such findings suggest that diversity becomes an increasingly prominent theme during the adult years, a point we will continue to focus on throughout this book.&#8221;</p>
<p>From <a href="http://www.amazon.com/Adult-Development-Aging-Biopsychosocial-Perspectives-ebook/dp/B005H8M3XM" rel="nofollow">Whitbourne &amp; Whitbourne</a>. Not bimodality, just greater variance. More:</p>
<p>&#8220;Over a 3-month period, even a moderate training program can augment muscle strength and maximal aerobic power by 20% or more, 25,26 — equivalent to a reversal of approximately 20 years of normal aging.26 [&#8230;] The muscle force and aerobic power required to undertake many of the tasks important to the independence of an elderly person (for example, rising from a chair or climbing a flight of stairs) are almost directly proportional to an individual’s body mass. Thus, a 10% reduction in body mass will effectively increase muscle strength and maximal aerobic power by some 10%, equivalent to a 10-year reversal of the effects of aging. [&#8230;] It has been suggested that declines in functional capacity with age reflect age-related reductions in physical activity. Inactivity has been estimated to account for 50% of the age-related loss in function.&#8221; </p>
<p>That is to say that to the extent that large differences exist, environmental factors &#8211; in particular physical activity &#8211; remain really important even in old age &#8211; i.e. it&#8217;s not just genetics. Quotes above are from <a href="http://books.google.dk/books/about/Gender_Physical_Activity_and_Aging.html?id=JgsqxTHeTiYC&amp;redir_esc=y" rel="nofollow">Gender, Physical Activity, and Aging</a>, by Shephard et al).</p>
<p>Also, on the same topic <a href="http://www.sciencedirect.com/science/article/pii/S0140673695915567" rel="nofollow">one meta-review</a> on Alzheimer&#8217;s in the very old found that 40% of those aged 95 suffered from Alzheimer&#8217;s. It was noteworthy that risk didn&#8217;t increase past that point (i.e. in people older than 95), but when 2 out of 5 of the people you&#8217;re looking at suffer from dementia I&#8217;m not sure &#8216;pretty healthy&#8217; is the best way to describe that population. The proportion of males having (prostate) cancer at that age is also, well, high&#8230;</p>
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		<title>By: Anthony</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-23053</link>
		<dc:creator><![CDATA[Anthony]]></dc:creator>
		<pubDate>Wed, 04 Dec 2013 16:03:10 +0000</pubDate>
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		<description><![CDATA[Maybe the witch hunters were all proto-Roissys, so a mechanism which let them keep the skinny women and burn the fat ones was a feature, not a bug?

More seriously, if someone had asked the witch-hunters why the fat ones were more likely to be found to be witches, they&#039;d say something about using witchcraft to unjustly provide themselves with more food, possibly by magically stealing it from the rest of the community.]]></description>
		<content:encoded><![CDATA[<p>Maybe the witch hunters were all proto-Roissys, so a mechanism which let them keep the skinny women and burn the fat ones was a feature, not a bug?</p>
<p>More seriously, if someone had asked the witch-hunters why the fat ones were more likely to be found to be witches, they&#8217;d say something about using witchcraft to unjustly provide themselves with more food, possibly by magically stealing it from the rest of the community.</p>
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		<title>By: Vertebrat</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-21885</link>
		<dc:creator><![CDATA[Vertebrat]]></dc:creator>
		<pubDate>Mon, 25 Nov 2013 21:42:31 +0000</pubDate>
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		<description><![CDATA[Rocket-propelled grenades are &lt;i&gt;so&lt;/i&gt; mainstream. They should shoot role-playing games instead: devise RPGs which will change the meaning of the “legitimate English words”, much as D&amp;D changed the meaning of “rogue”.]]></description>
		<content:encoded><![CDATA[<p>Rocket-propelled grenades are <i>so</i> mainstream. They should shoot role-playing games instead: devise RPGs which will change the meaning of the “legitimate English words”, much as D&amp;D changed the meaning of “rogue”.</p>
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		<title>By: Vertebrat</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-21884</link>
		<dc:creator><![CDATA[Vertebrat]]></dc:creator>
		<pubDate>Mon, 25 Nov 2013 21:34:12 +0000</pubDate>
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		<description><![CDATA[&lt;a href=&#039;http://www.peterleeson.com/Ordeals.pdf&#039; rel=&quot;nofollow&quot;&gt;Peter Leeson&#039;s account of trial by ordeal&lt;/a&gt; says the trials were easy to manipulate, and usually acquitted (in the case of trial by water, because the accused were usually skinny men, who reliably sink), so their main function was to intimidate superstitious defendants into confessing iff they were guilty.]]></description>
		<content:encoded><![CDATA[<p><a href='http://www.peterleeson.com/Ordeals.pdf' rel="nofollow">Peter Leeson&#8217;s account of trial by ordeal</a> says the trials were easy to manipulate, and usually acquitted (in the case of trial by water, because the accused were usually skinny men, who reliably sink), so their main function was to intimidate superstitious defendants into confessing iff they were guilty.</p>
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		<title>By: Scott Alexander</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-21413</link>
		<dc:creator><![CDATA[Scott Alexander]]></dc:creator>
		<pubDate>Thu, 21 Nov 2013 18:00:55 +0000</pubDate>
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		<description><![CDATA[The Equasy article certainly is. Are you saying his efforts to work on a new form of alcohol are as well?]]></description>
		<content:encoded><![CDATA[<p>The Equasy article certainly is. Are you saying his efforts to work on a new form of alcohol are as well?</p>
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		<title>By: Nestor</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-21404</link>
		<dc:creator><![CDATA[Nestor]]></dc:creator>
		<pubDate>Thu, 21 Nov 2013 16:46:20 +0000</pubDate>
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		<description><![CDATA[Catholics dude, we&#039;ll forgive anything.]]></description>
		<content:encoded><![CDATA[<p>Catholics dude, we&#8217;ll forgive anything.</p>
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		<title>By: Douglas Knight</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-21315</link>
		<dc:creator><![CDATA[Douglas Knight]]></dc:creator>
		<pubDate>Thu, 21 Nov 2013 03:17:34 +0000</pubDate>
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		<description><![CDATA[Scott&#039;s link and other news coverage I&#039;ve seen are not elaborate. Did Nutt himself write an article? Do you have a link?]]></description>
		<content:encoded><![CDATA[<p>Scott&#8217;s link and other news coverage I&#8217;ve seen are not elaborate. Did Nutt himself write an article? Do you have a link?</p>
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		<title>By: rsq</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-21314</link>
		<dc:creator><![CDATA[rsq]]></dc:creator>
		<pubDate>Thu, 21 Nov 2013 02:42:24 +0000</pubDate>
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		<description><![CDATA[I&#039;m told that Dr. Nutt&#039;s article is actually an elaborate satire designed to point out inconsistencies in British drug laws.  No idea of the truth of this.]]></description>
		<content:encoded><![CDATA[<p>I&#8217;m told that Dr. Nutt&#8217;s article is actually an elaborate satire designed to point out inconsistencies in British drug laws.  No idea of the truth of this.</p>
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		<title>By: Dave</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-21279</link>
		<dc:creator><![CDATA[Dave]]></dc:creator>
		<pubDate>Wed, 20 Nov 2013 22:00:26 +0000</pubDate>
		<guid isPermaLink="false">http://slatestarcodex.com/?p=1125#comment-21279</guid>
		<description><![CDATA[It reminds me of &lt;a href=&quot;http://slatestarcodex.com/2013/04/12/noisy-poll-results-and-reptilian-muslim-climatologists-from-mars/&quot; rel=&quot;nofollow&quot;&gt;“Well, on the one hand, Obama is the Anti-Christ. On the other, do I really want four years of Romney?”&lt;/a&gt;, which I often quote.

(Incidentally, googling &quot;lizardman Obama Romney antichrist&quot; was oddly enjoyable in its own right.)]]></description>
		<content:encoded><![CDATA[<p>It reminds me of <a href="http://slatestarcodex.com/2013/04/12/noisy-poll-results-and-reptilian-muslim-climatologists-from-mars/" rel="nofollow">“Well, on the one hand, Obama is the Anti-Christ. On the other, do I really want four years of Romney?”</a>, which I often quote.</p>
<p>(Incidentally, googling &#8220;lizardman Obama Romney antichrist&#8221; was oddly enjoyable in its own right.)</p>
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		<title>By: Yogonath</title>
		<link>http://slatestarcodex.com/2013/11/17/more-links-for-november/#comment-21242</link>
		<dc:creator><![CDATA[Yogonath]]></dc:creator>
		<pubDate>Wed, 20 Nov 2013 14:08:51 +0000</pubDate>
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		<description><![CDATA[Wasn&#039;t he running for a really minor office, community college board member or something like that? 26 votes probably was a significant chunk of the electorate.]]></description>
		<content:encoded><![CDATA[<p>Wasn&#8217;t he running for a really minor office, community college board member or something like that? 26 votes probably was a significant chunk of the electorate.</p>
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